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Pharmacokinetics of AuNPs Systemic distribution and tumor accumulation In the context of cancer therapy, AuNPs are generally believed to accumulate in tumor tissues due to the leaky vasculature and inefficient lymphatic drainage, a phenomenon known as the EPR effect

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Drug interactions Diclofenac: Diclofenac like other NSAIDs should not be administered concomitantly with: - Aspirin: because it alters the bioavailability of both drugs

The final summary information was shown in Supplementary Tables 13

Finally, we outline future directions and therapeutic implications, such as Siglec-8 agonism and dietary or glycan-based interventions, to modulate eosinophils in IBD