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Worlds Poultry Sci J (2018) 74(2):25164

doi: 10.1016/j.jcrc.2013.12.003

Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium

Chronic treatment with PARP inhibitors increased NAD + levels and mitochondrial respiration in 10-week-old mice and triggered UPR mt and increased mitochondrial respiration and lifespan in worms 109,257

Notably, specific ferroptosis inhibitors show efficacy not only in RF models but also in rodent models of kidney and liver cancer (195), underscoring ferroptosis in TECs as a therapeutically tractable node in fibrogenesis

When mitochondrial damage occurs, ROS production is significantly higher compared to normal physiological levels