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The Gro3p factor: Restoring NAD+/NADH homeostasis to ameliorate mitochondrial disease

instead, it produces reduced NADPH for cellular redox balance and ribose-5-phosphate for nucleic acid synthesis, respectively [30]

however, the ratio of homocysteine-to-methionine increased significantly (P=0.008)

In any case, all these mechanisms would explain the higher intramuscular fat content when feeding dietary L-Carnitine (Table 3), an opposite effect to the increased -oxidation of fatty acids at the mitochondrial level achieved by this compound