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Summary Keywords autologous organ-on-chip, precision medicine, disease modelling, tissue engineering, drug testing Citation Bisconti F, Abreu H, Nguyen TD, Stolfi F, Corbezzolo N, Gigli G, Raineri D, Cappellano G, Polini A, Gervaso F, Chiocchetti A and the FLAMIN-GO Consortium (2025) My cells, my model: immune-competent autologous organ-on-chip systems as a new paradigm in precision medicine

It is essential for shielding cells from oxidative damage and maintaining immunological function

Goda, N

In populations with schizophrenia, dysfunction in glutamate metabolism and decreased glutamate levels in the pre-frontal cortex have been reported.68 The addition of cysteine has been shown to modulate glutamate levels through glutamatecystine exchange, and GSH has been shown to modulate the binding of glutamate to N -methyl-d-aspartate receptors.69 N -acetylcysteine may be beneficial in the treatment of schizophrenia by targeting both oxidative stress and glutamatergic dysfunction, suggesting that the phenotype is a result of interactions of multiple neurotransmitter pathways70 that interact with oxidative and inflammatory systems, which are additionally implicated in the disorder

Trabi M, Schirra HJ, Craik DJ: Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes

State residence was associated with relapse within 1yr post-LT, with 18% relapse among out-of-state LT recipients