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Description

AKT activation because of PTEN loss upregulates xCT via GSK3/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

This level of resolution when dissecting the functionally relevant steps of a biochemical pathway across an organ was made more accessible through the use of direct GEFBs and inspires further questions

Metabolic imaging technology can identify patients with tumors with abnormal glutamine metabolism [16] to provide a basis for patients to target glutamine metabolism in cancer treatment

Injectable Forms : Intravenous or intramuscular glutathione provides direct access to the bloodstream

In combination with serine proteaseknockout mice, we delineate the roles of intestinal PAR2-activating proteases in postprandial incretin secretion and alterations in DIO