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Additionally, levels of oxidized glutathione (GSSG) and ATP, which is required for both -GCS and GSH formation, remained abundant following glucose deprivation in all cell lines

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Early intervention for G6PD deficiency may reduce the risk of vascular dysfunction and the incidence of CVD by correcting G6PD deficiency with small-molecule activators [12] or GSH precursors [10, 11] to prevent excessive OS