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Pharmaceuticals - another anthropogenic contaminant - studied by Diclofenac exposure in Gasterosteus aculeatus through metabolomics-based approaches showed that the antioxidant system is impacted in male sticklebacks (Lebeau-Roche et al., 2023)

I remember Sussman brought you into town

Niu et al., 2007

The skin epidermis contributes to the recruitment of inflammatory cells, and the cross-talk between epidermal cells and immune cells is likely to be important for the pathogenesis of psoriasis 24,25

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Another reaction that generates free radicals is the purine metabolism, where xanthine oxidase catalyses the conversion of hypoxanthine to xanthine and subsequently to uric acid, and during its re-oxidation, molecular oxygen is reduced to superoxide [31]