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Indoxyl sulfate activates NLRP3 inflammasome to induce cardiac contractile dysfunction accompanied by myocardial fibrosis and hypertrophy

doi: 10.17179/excli2019-1447

The mitochondria-specific autophagy process, also known as mitophagy, ultimately results in mitochondria engulfment and degradation [10, 11] which has been demonstrated experimentally where the systemic knockout of Parkin in mice resulted in elevated intracellular ROS levels in the VTA and a reduction in proteins involved in ETC and oxidative stress regulation [37]

Glutathione is cosmetically used to brighten and even out blotchy skin tone

In terms of wound dressings, hydrogels containing PPE offer significant advantages (Figure 5)

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