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doi: 10.1158/2326-6066.27950788 87 FangMYaoJZhangHSunJYinYShiHet al

Meanwhile, Gastrodia elata Blume polysaccharide was able to maintain gut health by regulating gut microbiota and increasing the production of beneficial metabolite such as short-chain fatty acids (SCFAs) ( Atractylodes macrocephala polysaccharide could reduce constipation-related symptoms by restoring the balance of gut microbiota and affecting related metabolic pathways to increase the production of SCFAs and up-regulate the expression levels of 5-hydroxytryptamine (5-HT) and chromogranin A (CgA) in constipated mice ( Trichosanthes kirilowii Maxim or Trichosanthes rosthornii Harms of the Cucurbitaceae family

Biotech.29: 135-136

The amino acids that exclusively interact with the drugs only in one protein can provide crucial insights into the specific interactions that facilitate the binding of these drugs to MRP1, in contrast to MRP7