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Y.et al (2015)

This reality directly influences how we must think about its application and administration, a topic we need to unpack with unflinching honesty

Receptor Supersensitivity Blockade In the landmark 1997 Sikiric study published in Biological Psychiatry (PMID: 9547930), mice pretreated with haloperidol (a dopamine antagonist) developed behavioral supersensitivity to amphetamine challenge