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We then performed single or combination treatment using the GLUT1 inhibitor BAY-876 and YBX1 inhibitor SU056

Analysis of the ER redox state with ERroGFP S4 Fluorescence images of HeLa cells stably expressing ERroGFP S4 were acquired by an LSM 510 META confocal microscope (Carl Zeiss, Germany) or an FV3000 confocal laser scanning microscope (Olympus, Tokyo, Japan) and quantified fluorescence intensity ratio (Ex405/Ex458 for the Carl Zeiss lsm) or (Ex405/Ex445 for the Olympus lsm) by using Image J as described previously 19

Statements Author contributions HH: Conceptualization, Investigation, Project administration, Validation, Writing original draft, Writing review & editing

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Toral Vaidya, MD MPH, FAAD, is a board-certified dermatologist based in New York City

K.MurugesanP.GurusamyM.WuD.ParkC