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The treatment involves a 300 mg/kg dose, administered in three separate doses over 21 hours

Delivered via AAV9, a single intracisternal dose enabled sustained brain expression for months and reduced pathological TDP-43 levels in translational mice (Val et al., 2025)

In contrast to the above results, in some cases GSTs were shown to contribute to resistance against powdery mildew

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Kreider RB, Miller GW, Schenck D, Cortes CW, Miriel V, Somma CT, Rowland P, Turner C, Hill D