10.1016/j.bbagen.2009.11.010 34 LeeH
About half of the patients with PCD start to see symptoms when they are very young, between three months and two years old
Common overlapping symptoms include: Changes in sleep patterns, ranging from insomnia to excessive sleeping Mood swings and emotional instability, which may fluctuate throughout the day Difficulty maintaining relationships, both personal and professional Problems at work or school, including decreased performance and attendance Loss of interest in previously enjoyed activities, often accompanied by social withdrawal Physical health deterioration, including changes in appetite and energy levels Social isolation and withdrawal, which can worsen both conditions These overlapping symptoms often mask underlying conditions
[Google Scholar] 97.Yarizadh H., Shab-Bidar S., Zamani B., Vanani A.N., Baharlooi H., Djafarian K
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Abbreviations ASD: Atrial septal defect CBP: Cardiopulmonary bypass CHD: Congenital heart disease CK-MB: Creatine kinase-MB ELISA: Enzyme-linked immunosorbent assay LVEF: Left ventricular ejection fraction MDA: Malondialdehyde SD: Standard deviation SOD: Superoxide dismutase TBARS: Thiobarbituric acid reactive substances VSD: Ventricular septal defect 2D-LV GLS: Two-dimensional left ventricular global longitudinal strain 2D-STE: Two-dimensional speckle tracking echocardiography References Ma M, Gauvreau K, Allan CK, Mayer JE Jr, Jenkins KJ (2007) Causes of death after congenital heart surgery