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doi: 10.1111/bph.12043

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Interestingly, high intracellular asparagine levels have recently been identified to be essential for breast cancer metastasis 51

Other factors that are implicated in the pathogenesis of glaucoma include vascular issues (leading to reduced blood flow to the optic nerve), mitochondrial dysfunction, excitotoxicity, and oxidative stress [70]

Instead, they step up the treatment by adding other conventional DMARDs (like sulfasalazine or hydroxychloroquine) or biologic agents (like TNF inhibitors) directly to the existing MTX regimen to achieve tighter disease control (Cohen & Mikuls, 2025)

Epitalon has been linked to better sleep quality by regulating the pineal glands production of melatonin, the hormone responsible for sleep-wake cycles