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10.5582/bst.2018.01082 Biosci

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In patients with renal dysfunction, peak concentrations of metabolites 4'-hydroxy- and 5-hydroxy-diclofenac were approximately 50% and 4% of the parent compound after single oral dosing compared to 27% and 1% in normal healthy subjects

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doi: 10.1007/s13679-023-00515-2

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In the past, the Schilling test was used, but is rarely conducted today because this test uses radioactive B12

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