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December 28, 2015

Healthy cells dynamically recruit chaperones, activate stress responses, mobilize UPS function, and initiate autophagy and mitophagy as integrated responses to stress

We established a novel multidisciplinary clinic aimed at enhancing the prevention and treatment of alcohol relapse and improving patient outcomes in high-risk liver transplant recipients

Disulfiram metabolites, including diethyldithiocarbamate (DDC), carbon disulfide (CS2), S-methyl N,N-diethylthiocarbamate sulfoxide (DETC-sulfoxide), S-methyl N,N-diethylthiocarbamate sulfone (DETC-sulfone), diethylthiomethylcarbamate, S-methyl-DDC, methyl diethylthiocarbamate sulfoxide, and methyl diethylthiocarbamate sulfone, play a crucial role in its pharmacological effects (PharmGKB, 2023)