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Butyrate acts as a HDAC inhibitor in immune cells, suppressing the expression of pro-inflammatory cytokines (TNF-, IL-6) and enhancing the integrity of epithelial tight junctions

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doi: 10.1016/j.scienta.2015.08.037 31 Cruz-CasasD

Regarding potential risks, trivalent chromium nutritional supplementsparticularly chromium picolinatehave a high safety profile within guideline-recommended doses