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The GSH-Fe-S cluster-OXPHOS axis GSH is indispensable for mitochondrial homeostasis and the biogenesis and stability of Fe-S clusters, thereby sustaining OXPHOS and cellular energy metabolism 16,17,203

Santos MN, Paushter DH, Zhang T, Wu X, Feng T, Lou J, Du H, Becker SM, Fragoza R, Yu H, et al

There remains much to learn about the roles, regulation, and therapeutic intervention of GPX4

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Conclusions : The current study doubles the exposure from the prior study and demonstrates that following 18 months of therapy, ABL was more effective than TPTD in reducing the incidence of hip fracture and nonvertebral fracture

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