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Its clinical trials for obesity did not meet efficacy endpoints, and it is currently classified as a chemical for research use only

A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient

Side Effects Semaglutide: Common Side Effects: Nausea Vomiting Diarrhoea Constipation Abdominal pain Less Common Side Effects: Headache Fatigue Dizziness Hypoglycaemia (especially in individuals with type 2 diabetes) Pancreatitis (rare but serious) Tirzepatide: Common Side Effects: Nausea Vomiting Diarrhea Constipation Abdominal pain Less Common Side Effects: Decreased appetite Dyspepsia (indigestion) Injection site reactions Hypoglycemia (more common when combined with insulin or sulfonylureas) Pancreatitis (rare but serious) Administration Semaglutide: Administered via injection

Post-Surgical & Post-Injury Spasms Muscle spasms after surgery are a recognized complication of orthopedic procedures, spinal surgeries, and abdominal operations

Vitamin B12 helps break down fats and proteins, which gives cells energy

Vitamin B12 is naturally found in animal products such as meat, fish, poultry, dairy, and eggs