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Enhanced Detoxification Glutathione is crucial for detoxifying harmful substances in the liver

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RNAsinPromega)

10.1038/s41580-023-00648-1 44 GanB

This study suggested that depletion of TMX2 using single guide (sg) RNA in K562 cells and mouse primary cortical neurons was sufficient to suppress PR 20 induced cellular toxicity (Kramer et al., 2018)