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Ethical Procurement and Transparency: All stem cells are obtained through voluntary, non-invasive donations with full ethical oversight, ensuring a sustainable and responsible supply chain that meets international bioethics standards

Microglial ferroptosis can activate neurotoxic astrocytes through pro-inflammatory signaling, and ferroptosis-related genes such as ALOX5/15 are highly enriched in microglia, yet this study does not establish whether ferroptosis is upstream in the cascade involving mitochondrial complex IV defects, oxidative stress, and neuroinflammation

J.SahuS.SunY

Yuan et al (171) reported that Keap1 mutations are relatively common in HNSCC, and that a mutation in or lack of Keap1 inhibits ferroptosis in HNSCC by increasing NAD(P)H quinone dehydrogenase 1 (NQO1) levels through NRF2 activation

Nose to brain delivery of phenytoin sodium loaded nano lipid carriers: formulation, drug release, permeation and in vivo pharmacokinetic studies

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