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Bariatric surgery, very low calorie diets, and even aggressive exercise regimens can all cause telogen effluvium through the same mechanisms

CXCR3, CXCR4, and CXCR5 enhance Th1 cells, lymphocytes, B cells, and T follicular helper (Tfh) cells into joint, respectively (100, 103)

Additionally, significant ROS signals were detected in the nuclei of cells exposed to hypertonic conditions, suggesting potential nuclear DNA damage [9]