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The challenge is getting it into cells via supplementation

3) substitution of a non- -amino acid (e.g., -amino acid or ?-amino acid) at the N-terminal

doi:10.3390/ijms27062876 Note: every reference above is a study of a single compound

In a study, it was reported that oral administration of 1.5 g MSM to rats for 90 days did not cause any side effects and mortality [47]

The complex, multi-factorial pathogenesis of SAH, with intertwined pathways, strongly suggests that single-agent therapies may be insufficient to achieve sustained clinical benefit [14,31]