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Efficacy and safety of subcutaneous tabalumab in patients with systemic lupus erythematosus: results from ILLUMINATE-1, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study

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HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours

doi: 10.1007/s10545-016-9950-0 80

Research suggests glutathione levels decline with age, chronic inflammation, and metabolic stress, making biomarker assessment clinically relevant for personalized evaluation

Michael's Hospital, Unity Health Toronto, (3)Li Ka Shing Knowledge Institute, St Michaels Hospital, Unity Health Toronto, (4)University of Toronto, (5)Dept of Medicine and Ihpme, University of Toronto, (6)Toronto Centre for Liver Disease, University of Toronto, Toronto, Ontario, Canada Background: Acute kidney injury (AKI) is a frequent complication in hospitalized patients with cirrhosis and results in significant morbidity and mortality