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For this reason, intense photophobia develops even prior to the onset of head pain and other typical symptoms

Its apparent capacity to modulate sleep-wake cycles, stress hormone secretion, and oxidative stress responses within a single nine-amino acid structure makes it a particularly compact and multifunctional subject for laboratory investigation into neuropeptide signaling complexity

Research should be limited to in vitro studies and approved preclinical laboratory models

The Outline

Pharmacology Biochemistry and Behavior, 13(6), 895900

Despite promising evidence in preclinical studies, few neurotrophic factors have been tested in clinical trials for TBI