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The response is cumulative, building across the 4 doses and continuing into the weeks after the final injection

10.1111/j.0954-6820.1968.tb02452.x

After reconstitution: Store at 28 C , protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling

In fact, it was reported that extracellular adenosine can be generated from both NAD and ATP degradation via a cascade of events that includes CD38 ecto-NADase, and CD39 ecto-ATPase activity

Animal data is more robust

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