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This comprehensive search utilized databases such as PubMed, Scopus, and Web of Science, with keywords including ME/CFS, Gut-Brain Axis, Gut Health, Intestinal Dysbiosis, Microbiome Dysbiosis, Pathophysiology, and Therapeutic Approaches. Where possible, insights from clinical trials and observational studies were included to enrich the findings

260 Furthermore, the phagocytic capacity of alveolar macrophages and neutrophils, which are responsible for pathogen clearance, diminishes in elderly individuals, thereby heightening their susceptibility to pulmonary infections

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Guidelines on management of cyclic vomiting syndrome in adults by the American Neurogastroenterology and Motility Society and the Cyclic Vomiting Syndrome Association