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Methods: Quintuple Serpina1ae knockout (A1AT KO) mice, human IL-32 transgenic (hIL-32 Tg) mice, and hIL-32 Tg/A1AT KO mice were fed with fast food diet (FFD)

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Endogenous Production of Reactive Oxygen Species and its Biological Effects in Asthma Inflammatory cells (such as activated eosinophils, neutrophils, monocytes, and macrophages) and resident cells (such as epithelial and smooth muscle cells) can generate reactive oxygen species (ROS) [1214]