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The following have been shown to shift estrogen metabolism toward the 2-hydroxyestrone pathway[2]: Exercise and weight loss Isoflavones such as soy and flaxseed Omega-3 fatty acids Green tea polyphenol Cruciferous vegetables and broccoli derivatives, including indole-3-carbinol (I3C) and diindolylmethane (DIM, result of I3C after activation by stomach acid) A healthy lifestyle that allows for a normal weight helps to decrease the risk of insulin resistance from metabolic syndrome

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However, most of the time, this medication would be given at the end of pregnancy to promote and accelerate fetal lung maturation in the case of preterm labor and delivery, Dr

doi:10.1007/s00253-004-1751-y Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., & Durbin, R