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While efficacy was demonstrated in an in vitro model [37], such benefit was not observed in a volunteer study of subjects with nitrite-induced methemoglobinemia [38]

Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and -synuclein oligomerization in a subacute MPTP mouse model of Parkinsons disease

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The SSP is aberrantly activated in a variety of malignant tumors and promotes tumor progression through multi-dimensional mechanisms