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Gilley J, Coffer PJ, Ham J: FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

Toxins now are well established to impair the ability of our mitochondria, the batteries in every cell, to create energy

doi: 10.2147/DMSO.S304817 232 WenjingXPeiWYueshiMYongLWeiqinZLipingG

Consistent with this, TCA cycle intermediate labeling patterns revealed that ACT impairs mitochondrial glucose oxidation in WT cells, while loss of ATP6AP1 partially restores this capacity