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Consider B 12 supplementation without testing in asymptomatic patients with risk factors for B 12 deficiency (see Table 1: Patient Risk Factors Associated with B 12 Deficiency)

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Treatment of adipocytes isolated from HSL-null mice with the beta-adrenergic agonist isoproterenol causes enhanced lipolysis, albeit at a blunted level compared with adipocytes from wild-type animals (91)

In a typical Western diet, a person obtains approximately 5 to 15 mcg of vitamin B 12 daily, much more than the recommended daily allowance of 2 mcg