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Disturbances in insulin-glucose metabolism in patients with advanced renal disease with and without diabetes

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Two phase 2 trials, including older adults up to 75 years, have recently been published assessing the impact of retatrutide on patients with overweight and obesity, with or without T2D, respectively [75, 118]

Retrieved July 10, 2025, from Korenevsky, A

It combines two hormones: semaglutide (a GLP-1 receptor agonist) and cagrilintide (an amylin analog)

In vitro, NKG2D CAR-T cells selectively eliminate senescent fibroblasts induced by different stresses as well as in vivo, in mice and non-human primate aged models where the effects of this cell therapy are significant without any toxicity observed