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Cardiovascular complications in chronic kidney disease: a review from the European renal and cardiovascular medicine working Group of the European Renal Association

In 2 patients MRI showed T2/FLAIR hyperintensity in bilateral basal ganglia

Common contributors include: Iron deficiency (even mild cases) Pregnancy , especially in the third trimester Chronic conditions like diabetes, kidney disease, or peripheral neuropathy Certain medications (e.g., antidepressants, antihistamines, antipsychotics) Genetic predisposition RLS can run in families Can You Prevent Restless Leg Syndrome

Seek prompt medical attention for trouble breathing, facial or throat swelling, fainting, chest pain, severe abdominal pain, persistent vomiting, neurological symptoms, signs of infection, or another severe or unexpected reaction

In both cases, the data are insufficient to support clinical claims

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