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Early symptoms of MS include: Chronic fatigue Difficulty walking or loss of balance Numbness and tingling in the extremities Muscle pain, stiffness or spasms Vision problems Slowed cognition Motion sickness, nausea and vomiting Progression of Multiple Sclerosis Multiple sclerosis is a progressive disorder with four identified phases: Clinically isolated syndrome (CIS) is when MS symptoms first appear, characterized by inflammatory demyelination

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There is a correlation between the expression of lncRNA TDRG1 and another lncRNA, H19, in TGCTs