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Description

When glycine binds to inhibitory glycine receptors (chloride-channel complexes), it causes an influx of chloride ions into neurons, hyperpolarizing the cell membrane and thereby reducing neuronal excitability

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53(3):52337 Mousseau M, Burma NE, Lee KY, Leduc-Pessah H, Kwok CHT, Reid AR, OBrien M, Sagalajev B, Stratton JA, Patrick N, Stemkowski PL, Biernaskie J, Zamponi GW, Salo P, McDougall JJ, Prescott SA, Matyas JR, Trang T (2018) Microglial pannexin-1 channel activation is a spinal determinant of joint pain