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Hydroxocobalamin is an antidote that seems to have many of the characteristics of the ideal cyanide antidote: rapid onset of action, neutralizes cyanide without interfering with cellular oxygen use, tolerability and safety profiles conducive to prehospital use, safe for use with smoke-inhalation victims, not harmful when administered to non-poisoned patients, easy to administer (Class IV)

Outside Resources Homocystinuria caused by cobalamin cofactor metabolism (cbl) defect occurs when the body cannot properly process cobalamin (vitamin B12)

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The MOTS-c 5-amino-1MQ stack works through different mechanismsAMPK activation and NNMT inhibitionthat increase energy expenditure and fat oxidation without primarily targeting appetite

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