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The review highlights the critical role of astrocyte-neuron metabolic coupling, particularly through the lactate shuttle and glutathione metabolism, in maintaining neuronal homeostasis and facilitating synaptic function

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HO-1 induction also brings negative effects, inducing ferroptosis, CO toxicity

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Clinical characteristics of patients in the study Figure 2 Discussion This is the first study examining the long-term treatment response of neuropathic pain with BoNT

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