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Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies

Compared with mice transplanted with the first trimester of pregnancy microbiota, mice transplanted with the third trimester of microbiota showed significant weight gain, insulin resistance, and greater inflammatory response (Koren et al., 2012)

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