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The increased expression of immune checkpoint ligand levels in TAMs (such as PD-L1 and PD-L2, etc.) can directly inhibit the activity of T cells

Additionally, polyphenols chelate metal ions like iron and copper, which catalyze the formation of highly reactive hydroxyl radicals through Fenton reactions, further reducing oxidative damage (Fraga et al

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If you are worried that you could get Barretts esophagus, speak to your gastroenterologist