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10.1212/01.wnl.0000134666.64593.ba 47 YermakovL

Jun 17 2002;86(12):1854-1857

In addition to the challenge of creating metal-limiting conditions, many metalloenzymes can interact with more than one transition metal with variable effects on activity

In hepatocellular carcinoma, hypoxia upregulates SLC7A11 by inhibiting the expression of methyltransferase 14 (METTL14), further suppressing ferroptosis (211)