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Kakkar and co-authors prepared the tetrahydrocurcumin (THC) loaded lipidic nanoparticles by microemulsification technique [90]

6 Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116023, Peoples Republic of China *These authors contributed equally to this work Correspondence: Hailong Chen, Email [email protected] Abstract: The gut microbiota and its metabolites are bi-directionally associated with various human illnesses, which has received extensive attention