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& Regehr, W

Phase 3 confirms benefits and compares the new drug with existing treatments in a larger population

Free radicals are atoms, molecules, or ions with unpaired electrons, making them highly unstable and reactive in chemical interactions with other molecules

Recent structures of transhydrogenase holoenzymes suggest new mechanistic details, how the long-distance coupling between hydride transfer in the peripheral nucleotide binding sites and the membrane-localized proton transfer occurs that now must be tested experimentally

10.1038/ncomms11624 78 Koch-HenriksenN.SorensenP

Butola LK, Kute PK, Anjankar A, Dhok A, Gusain N, Vagga A