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Therapeutic targeting of ERAD and ER stress in metabolic diseases 4-Phenylbutyric Acid (4-PBA) Chemical chaperones such as 4-PBA have demonstrated beneficial effects in mouse models of obesity and diabetes, normalizing hyperglycemia and restoring systemic insulin sensitivity

Blaylock RL, Maroon J

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Always discuss your alcohol use with your doctor, especially if you are being treated for a deficiency related to poor nutrition or liver function