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Mitochondrial dysfunction is also considered in migraine patients (143)

Seekpeptides AHK-Cu shifts the apoptotic balance toward cell survival by increasing anti-apoptotic Bcl-2 expression, reducing pro-apoptotic Bax, and markedly lowering levels of cleaved caspase-3 and PARP fragmentation by 42.7% and 77.5%, respectively

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However, the data indicates that this peptide might not significantly affect the frequency of growth hormone pulses or the peak levels reached during each pulse