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Several studies have contributed to the current understanding of how mutations in the SARS-CoV-2 spike protein affect neutralization and emergence of new strains, which include studies of traditional escape mutation, targeted characterization of particular mutations, and wider investigations of large numbers of circulating variants [16]

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To maintain homeostasis, organisms and cells developed a sophisticated enzymatic and non-enzymatic antioxidant defense system including catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) that counteracts excessive ROS levels

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Simulation and prediction of the drugdrug interaction potential of naloxegol by physiologically based pharmacokinetic modeling