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4.2.3 Systemic inflammatory response Intestinal barrier failure leads to systemic low-grade chronic inflammation, a key pathological bridge between gut and brain

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In addition, these changes cause a reduction of cerebral blood flow (CBF) and synaptic dysfunction with the development of neurodegeneration and cognitive impairment (Kamat et al

Ipamorelin , a selective GHSR-1a (ghrelin receptor) agonist , triggers a separate GH pulse without affecting cortisol or prolactin

Richardson, T