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Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, et al

This is a stark contrast to the typically slow improvement of polyneuropathy in POEMS, and could imply that at least part of the underlying mechanism causing neuropathy in POEMS may be related to vitamin B6 deficiency, and that an evaluation of vitamin levels in POEMS may be currently underappreciated

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The nasal spray format is currently being explored for its potential to facilitate efficient absorption pathways in research models under controlled conditions

Furthermore, Renerve Plus Injection is formulated with a combination of other important vitamins that work together to enhance the immune system, boost metabolism, and support the proper functioning of the nervous system

Eligibility to participate was assessed based on medical history, physical examination, routine clinical laboratory tests, urine pregnancy tests for females, and inclusion/exclusion criteria (Table S1)