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Cancer Letters 621, 2025

Weiler-Normann C, Schramm C, Quaas A, Wiegard C, Glaubke C, Pannicke N

Aging is complicated There's still a lot of work to be done before this kind of research can be applied to humans

van den Berg M, Boers GHJ, Franken DG, Blom HJ, van Kamp GJ, Jakobs C, Rauwerda JA, Kluft C, and Stehouwert CDA (1995)

In this pathology, IGF-I levels diverge between studies, from increased to decreased IGF-I concentrations[330332], probably due to differences in samples origin (serum/cerebrospinal fluid vs spinal cord/musculoskeletal) and could be explained as a physiological defensive mechanism promoted in response to the neural degeneration and/or muscle atrophy