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Many peptides are still experimental, used offlabel or restricted to research settings

miR-93 is able to reduce the levels of Beclin-1, ATG5, ATG4B, and p62 in order to inhibit autophagy and enhance the effectiveness of therapy in GBM [181]

379 In PGC-1 knockout mouse models, DA neurons exhibit increased sensitivity to the neurotoxin MPTP, potentially due to the lack of PGC-1-mediated induction of antioxidant responses

doi: 10.1038/npp.2012.112 254 MenkeABinderEB

Disruption of the gut microbial communities in Crohns patients has been previously reported, however, these disruptions may either exacerbate disease pathologies or be a consequence of the chronic gut inflammation arising from genetic abnormalities that result in dysfunctional immune signalling

16 (11), 68236831 (2016) K